fluorouracil

Contraindication/Precautions

Contraindicated in:

• Hypersensitivity
• Dihydropyrimidine dehydrogenase deficiency (patients at ↑ risk of 5–FU toxicity)
• OB: Lactation: Pregnancy or lactation.

Use Cautiously in:

• Infections
• Depressed bone marrow reserve
• Other chronic debilitating illnesses
• Obese patients, patients with edema or ascites (dose should be based on ideal body weight).