Assessment
Monitor mood changes. Assess patient for frequency of obsessive-compulsive behaviors. Note degree to which these thoughts and behaviors interfere with daily functioning. Inform health care professional if patient demonstrates significant increase in anxiety, nervousness, or insomnia
Assess for suicidal tendencies, especially during early therapy. Restrict amount of drug available to patient. Risk may be increased in children, adolescents, and adults C24 yrs. After starting therapy, children, adolescents, and young adults should be seen by health care professional at least weekly for 4 wk, every 3 wk for next 4 wk, and on advice of health care professional thereafter
Monitor appetite and nutritional intake. Weigh weekly. Report significant changes in weight. Adjust diet as tolerated to support nutritional status
Assess for serotonin syndrome (mental changes [agitation, hallucinations, coma], autonomic instability [tachycardia, labile blood pressure, hyperthermia], neuromuscular aberations [hyperreflexia, incoordination], and/or GI symptoms [nausea, vomiting, diarrhea]), especially in patients taking other serotonergic drugs (SSRIs, SNRIs, triptans)
Toxicity and Overdose Common symptoms of toxicity include drowsiness, vomiting, diarrhea, and dizziness. Coma, tachycardia, bradycardia, hypotension, ECG abnormalities, liver function abnormalities, and convulsions may also occur. Treatment is symptomatic and supportive
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