Route/Dosage

• Note: Doses of fosphenytoin are expressed as phenytoin sodium equivalents [PE]

• IV (Adults): 15–20 mg PE/kg.

• IV, IM (Adults and Children > 16 yr):
Loading dose—10–20 mg PE/kg.
Maintenance dose—4–6 mg PE/kg/day.

• IV, IM (Children 10–16 yr): 6–7 mg PE/kg/day.

• IV, IM (Children 7–9 yr): 7–8 mg PE/kg/day.

• IV, IM (Children 4–6 yr): 7.5–9 mg PE/kg/day.

• IV, IM (Children 0.5–3 yr): 8–10 mg PE kg/day.

• IV, IM (Infants): 5 mg PE kg/day.

• IV, IM (Neonates): 5–8 mg PE/kg/day.

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