Implementation

• Patient should be maintained on a stable dose for a minimum of 4 weeks prior to increasing dose

» If dose has been interrupted for several days or longer, restart at the lowest dose and escalate to the current dose

• PO: Administer twice daily, preferably with morning and evening meal. Administration with food, the use of antiemetic medications, and ensuring adequate fluid intake may decrease nausea and vomiting

» Administer extended-release capsules in the morning, preferably with food. Razadyne XR can be opened and sprinkled on applesauce or yogurt; should be consumed within 10 min

• Use pipette provided with oral solution to administer accurate amount

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