Davis's Drug Guide

ketorolac

Implementation

Do not confuse Toradol (ketorolac) with Torecan (thiethylperazine) or tramadol (Ultram)

» Administration in higher-than-recommended doses does not provide increased effectiveness but may cause increased side effects. Duration of ketorolac therapy, by all routes combined, should not exceed 5 days Use lowest effective dose for shortest period of time

» Coadministration with opioid analgesics may have additive analgesic effects and may permit lower opioid doses

PO: Ketorolac therapy should always be given initially by the IM or IV route. Use oral therapy only as a continuation of parenteral therapy



IV Adminstration:

Direct IV:
Administer undiluted. Concentration: 15–30 mg/ml.

Rate:
Administer over at least 15 sec

Syringe Compatibility:

» sufentanil

Syringe Incompatibility:

» haloperidol

» hydroxyzine

» nalbuphine

» prochlorperazine

» promethazine

» thiethylperazine

Y-Site Compatibility:

» cisatracurium

» dexmedetomidine

» fentanyl

» hydromorphone

» methadone

» morphine

» remifentanil

» sufentanil

Y-Site Incompatibility:

» azithromycin

» fenoldopam

Solution Compatibility:

» D5/0.9% NaCl

» D5W

» Ringer's injection

» lactated Ringer's injection

» 0.9% NaCl



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