levetiracetam

Implementation

• Do not confuse Keppra (levetiracetam) with Kaletra (lopinavir/ritonavir).

» IV doses should be used temporarily when oral route is not feasible. To convert IV to PO, equivalent dose and frequency may be used.

• PO: May be administered without regard to meals.

• Administer tablets whole; do not administer partial tablets. Do not break, crush, or chew XR tablets.

• Pedi: Patients <20 kg should receive oral solution. Administer with calibrated measuring device for accurate dose.

• Discontinue gradually to minimize the risk of increase in seizure frequency.

• pH:
5.5.

• Intermittent Infusion:

Diluent: Dilute dose in 100 mL of 0.9% NaCl, D5W, or LR. Do not administer solutions that are cloudy or contain particulate matter.

• Rate:
Infuse over 15 min.

• Y-Site Compatibility:

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