Davis's Drug Guide

levetiracetam

Pharmacokinetics

Absorption: Rapidly and completely absorbed following oral administration

Distribution: Unknown

Metabolism and Excretion: 66% excreted unchanged by the kidneys; some metabolism by the liver (metabolites inactive)

Half-life: 7.1 hr (increased in renal impairment)

TIME/ACTION PROFILE (blood levels)

ROUTEONSETPEAKDURATION
POrapid1–1.5 hr†12 hr

†1 hr in the fasting state, 1.5 hr when taken with food



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