Davis's Drug Guide

LIDOCAINE

Assessment

Antiarrhythmic

Monitor ECG continuously and blood pressure and respiratory status frequently during administration



Anesthetic

• Assess degree of numbness of affected part



Lab Test Considerations

• Serum electrolyte levels should be monitored periodically during prolonged therapy

» IM administration may cause CPK levels



Toxicity and Overdose

• Serum lidocaine levels should be monitored periodically during prolonged or high-dose IV therapy. Therapeutic serum lidocaine levels range from 1.5 to 5 mcg/ml

» Signs and symptoms of toxicity include confusion, excitation, blurred or double vision, nausea, vomiting, ringing in ears, tremors, twitching, seizures, difficulty breathing, severe dizziness or fainting, and unusually slow heart rate

» If symptoms of overdose occur, stop infusion and monitor patient closely



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