lidocaine/prilocaine

Contraindication/Precautions

Contraindicated in:

• Hypersensitivity to lidocaine, prilocaine, or any other amide-type local anesthetic;

• Hypersensitivity to any other product in the formulation;

• Should not be applied to middle ear, mucous membranes, or broken/inflamed skin;

• Pedi: Congenital or idiopathic methemoglobinemia;

• Infants <1 mo if gestational age is <37 weeks;

• Infants <12 mo receiving methemoglobin-inducing agents.

• Repeated use or use on large areas of skin (more likely to result in systemic absorption);

• Acutely ill, or debilitated patients (↑ risk of absorption and systemic effects);

• Severe liver disease;

• Any conditions associated with methemoglobinemia (including glucose-6-phosphate dehydrogenase deficiency);

• OB: Use only if clearly needed;

• Lactation: Usually compatible with breastfeeding (AAP);

• Pedi: Area/duration of treatment should be limited in neonates and children <20 kg or 37 weeks gestation (↑ susceptibility to methemoglobinemia);

• Geri: May have ↑ absorption and risk of systemic effects.