Areas of skin rash, abrasion, or inflammation (absorption is increased);
History of seizures;
Lactation: Potentially toxic to infants; may ↓ milk supply;
Pedi: Premature neonates (↑ risk of CNS toxicity).Use Cautiously in:
Patients with skin conditions (↑ risk of systemic absorption);
OB: Do not exceed recommended dose; do not use >2 courses of therapy;
Pedi: Geri: Children ≤2 yr and geriatric patients (↑ risk of systemic absorption and CNS side effects).