Interactions

Drug-Drug

• May prolong the action of neuromuscular blocking agents

• risk of neurologic toxicity with haloperidol or molindone

• Diuretics, methyldopa , probenecid, fluoxetine, and NSAIDs may risk of toxicity

• Blood levels may be by ACE inhibitors

• Lithium may effects of chlorpromazine

• Chlorpromazine may mask early signs of lithium toxicity

• Hypothyroid effects may be additive with potassium iodide or antithyroid agents

• Aminophylline, phenothiazines, and drugs containing large amounts of sodium renal elimination and effectiveness

• Psyllium can lithium levels

Drug-Natural Products
Caffeine-containing herbs (cola nut, guarana, mate, tea, coffee) may lithium serum levels and efficacy

Drug-Food
Large changes in sodium intake may alter the renal elimination of lithium. sodium intake will renal excretion

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