Davis's Drug Guide

meperidine

Route/Dosage

PO, IM, SC, IV (Adults):
Analgesia—50–150 mg q 3–4 hr.
Analgesia during labor—50–100 mg IM or subcut when contractions become regular; may repeat q 1–3 hr.
Preoperative sedation—50–100 mg IM or subcut 30–90 min before anesthesia.

PO, IM, SC, IV (Children):
Analgesia—1–1.5 mg/kg q 3–4 hr (should not exceed 100 mg/dose).
Preoperative sedation—1–2 mg/kg 30–90 min before anesthesia (not to exceed adult dose).

IV (Adults): 15–35 mg/hr as a continuous infusion;
PCA—10 mg initially; with a range 0f 1–5 mg/incremental dose, recommended lockout interval is 6–10 min (minimum 5 min).

IV (Children):
Continuous infusion—0.5–1 mg/kg loading dose followed by 0.3 mg/kg/hr, titrate to effect up to 0.5–0.7 mg/kg/hr.



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