General

High Alert Medication: This medication bears a heightened risk of causing significant patient harm when it is used in error.

Pronunciation
meth-o-TREX-ate

Trade Name(s)

• amethopterin

• Folex

• Folex PFS

• Rheumatrex

• Trexall

Pregnancy Category
Category X

Ther. class.
antineoplastics
antirheumatics
(DMARDs)
immunosuppressants

Pharm. class.
antimetabolites

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