Assessment

• Monitor blood pressure, intake and output, and daily weight, and assess feet, legs, and sacral area for edema daily

» Assess patient, especially if taking digoxin, for anorexia, nausea, vomiting, muscle cramps, paresthesia, and confusion. Notify physician or other health care professional if these signs of electrolyte imbalance occur. Patients taking digoxin are at risk of digoxin toxicity because of the potassium-depleting effect of the diuretic

» Assess patient for allergy to sulfonamides

• Monitor blood pressure before and periodically during therapy

» Monitor frequency of prescription refills to determine compliance

• Monitor electrolytes (especially potassium), blood glucose, BUN, and serum creatinine and uric acid levels before and periodically during therapy

» May cause in serum and urine glucose in diabetic patients

» May cause an in serum bilirubin, calcium, creatinine, and uric acid, and a in serum magnesium, potassium, and sodium and urinary calcium concentrations

» May cause serum protein-bound iodine (PBI) concentrations

» May cause serum cholesterol, low-density lipoprotein, and triglyceride concentrations

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