morphine

Contraindication/Precautions

Contraindicated in:

• Hypersensitivity;

• Some products contain tartrazine, bisulfites, or alcohol and should be avoided in patients with known hypersensitivity.

• Head trauma;

• ↑ intracranial pressure;

• Severe renal, hepatic, or pulmonary disease;

• Hypothyroidism;

• Seizure disorder;

• Adrenal insufficiency;

• History of substance abuse;

• Undiagnosed abdominal pain;

• Prostatic hyperplasia;

• Patients undergoing procedures that rapidly ↓ pain (cordotomy, radiation); long-acting agents should be discontinued 24 hr before and replaced with short-acting agents;

• Geri: Geriatric or debilitated patients (dose reduction suggested);

• OB: Lactation: Avoid chronic use; has been used during labor but may cause respiratory depression in the newborn;

• Pedi: Epidural liposomal injection only-not recommended;

• Pedi: Neonates and infants <3 mo (more susceptible to respiratory depression);

• Pedi: Neonates (oral solution contains sodium benzoate which can cause potentially fatal gasping syndrome).