Route/Dosage

• PO (Adults and Children >50 kg): Hyperuricemia—250 mg twice daily for 1 wk; ↑ to 500 mg twice daily, then may ↑ by 500 mg/day every 4 wk (not to exceed 3 g/day).Augmentation of penicillins/cephalosporins—500 mg 4 times daily. Single-dose therapy of gonorrhea—1 g with amoxicillin or penicillin.

• PO (Children 2–14 yr and C50 kg): 25 mg/kg (700 mg/m²) initially; then 10 mg/kg (300 mg/m²) 4 times daily.

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