Assessment

Gout

• Assess involved joints for pain, mobility, and edema throughout course of therapy

» Monitor intake and output ratios. Fluids should be encouraged to prevent urate stone formation (2000–3000 mL/day). Alkalinization of the urine with sodium bicarbonate, potassium citrate, or acetazolamide may also be used for this purpose

• CBC, serum uric acid levels, and renal function should be monitored routinely during long-term therapy

» Serum and urine uric acid determinations may be measured periodically when probenecid is used to treat hyperuricemia

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