Pharmacokinetics
Absorption: Well absorbed following oral administration
Distribution: Widely distributed; crosses the blood-brain barrier
Metabolism and Excretion: Metabolized by the liver; <5% excreted unchanged by the kidneys; some respiratory elimination as methane and carbon dioxide
Half-life: 1 hr
TIME/ACTION PROFILE (effects on blood counts)
| ROUTE | ONSET | PEAK | DURATION |
| PO | 14 days | 28 wk | 28 days or more (up to 6 wk) |
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