Davis's Drug Guide

tocainide

Pharmacokinetics

Absorption: Well absorbed after oral administration

Distribution: Widely distributed; crosses the blood-brain barrier

Metabolism and Excretion: Partially metabolized by the liver. 30–50% excreted unchanged by the kidneys

Half-life: 11–23 hr

TIME/ACTION PROFILE (antiarrhythmic effects)

ROUTEONSETPEAKDURATION
PO30–60 min0.5–2 hr8–12 hr



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