Contraindication/Precautions

Contraindicated in:

• Hypersensitivity

• Lactation

• Renal impairment (dosage reduction recommended if CCr <70 ml/min/1.73 m²)

• Hepatic impairment

• Dehydration

• OB: Use only if maternal benefit outweighs fetal risk

• Lactation: Discontinue drug or bottle feed.

• Pedi: Children are more prone to oligohydrosis and hyperthermia; safety in children <2 yr not established

• Geri: Consider age-related decrease in renal/hepatic impairment, concurrent disease states and drug therapy

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