Davis's Drug Guide

topiramate

Interactions

Drug-Drug

• Blood levels and effects may be by phenytoin, carbamazepine, or valproic acid

• May blood levels and effects of phenytoin or amitriptyline

• May blood levels and effects of hormonal contraceptives, risperidone, lithium or valproic acid

risk of CNS depression with alcohol or other CNS depressants

Carbonic anhydrase inhibitors (acetazolamide) may risk of kidney stones

• Concurrent use with valproic acid may risk of hyperammonemia/encephalopathy



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