Interactions

Drug-Drug

• Blood levels and effects may be by phenytoin, carbamazepine, or valproic acid

• May blood levels and effects of phenytoin or amitriptyline

• May blood levels and effects of hormonal contraceptives, risperidone, lithium or valproic acid

• risk of CNS depression with alcohol or other CNS depressants

• Carbonic anhydrase inhibitors (acetazolamide) may risk of kidney stones

• Concurrent use with valproic acid may risk of hyperammonemia/encephalopathy

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