Assessment

Seizures

• Assess location, duration, and characteristics of seizure activity

• Assess pain location, intensity, duration, and associated symptoms (photophobia, phonophobia, nausea, vomiting) during migraine attack. Monitor frequency and intensity of pain on pain scale

• Administer Young Mania Rating Scale (YMRS) or similar tool to evaluate manic symptoms at baseline and over time in patients

• Monitor CBC with differential and platelet count before therapy to determine baseline levels and periodically during therapy. Frequently causes anemia

» Hepatic function should be monitored periodically throughout therapy. May cause AST and ALT levels

» Evaluate serum bicarbonate prior to and periodically during therapy. If metabolic acidosis occurs, dosing taper or discontinuation may be necessary

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