**Off Market Drug**
This medication is no longer available in the United States. Information provided here is for reference purposes only.
This monograph describes a medication approved for use in Canada by the Therapeutic Products Directorate, a division of Health Canada’s Health Products and Food Branch. The medication is not approved by the United States Food and Drug Administration; however, a similar formulation carrying a different generic or brand name might be available in the US.
Local treatment of ocular infections due to susceptible organisms including blepharitis, conjunctivitis, corneal injuries, corneal ulcers, meibomianitis, ocular infections, following foreign body removal (prevention of infection).
Inhibits protein synthesis in susceptible bacteria by binding to ribosomal subunits; not active against fungi, viruses, and most anaerobic bacteria. Active against Staphylococcus aureus, the proteus group of bacteria, coliforms, and Pseudomonas aeruginosa.
Erradication/prevention of infection.
Absorption: Poorly absorbed following oral administration. Minimal systemic absorption following ophthalmic use.
Metabolism and Excretion: Unknown.
|ophth||rapid||unknown||1–6 hr (longer for opth ointment)|
Use Cautiously in:
Local: allergic cutaneous reactions
Misc: overgrowth of nonsusceptible organisms (prolonged use)
* CAPITALS indicate life-threatening.
Underline indicate most frequent.
Ophth: (Adults) Ophthalmic solution–1–2 drops every 1–2 hr acutely for 2–3 days, then 1–2 drops 3–4 times daily; ophthalmic ointment–apply 2–3 times daily or use at bedtime if solution has been used during the day.
Ophthalmic solution: 5 mg/ml in 8-mL bottles
Ophthalmic ointment: 5 mg/g in 5-g tubes
In Combination with: phenylephrine (Soframycin Nasal Spray), gramicidin (Soframycin Skin Ointment)
Instruct patient on proper technique for applying drops or ointment.
Resolution of signs and symptoms of eye infection.
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