Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.
Inositol is an essential component of cell membrane phospholipids. It is a constituent of the intracellular phosphatidyl inositol second messenger system which is linked to serotonin, norepinephrine, and cholinergic receptors. It may have similar benefits as SSRIs in panic disorder and OCD. It induces ovulation by improving insulin sensitivity in women with polycystic ovary syndrome. Inositol helps psoriasis triggered by lithium through an unknown mechanism. In infants with RDS, inositol lowers inspiratory oxygen requirements, mean airway pressure, and bronchopulmonary dysplasia incidence in premature infants not receiving surfactant when compared to placebo.
Metabolism and Excretion: Unknown.
Use Cautiously in:
CNS: headache, dizziness, fatigue
* CAPITALS indicate life-threatening.
Underline indicate most frequent.
Natural Drug Interaction
PO (Adults) Panic disorder– 12–18 grams/day. OCD– 18 grams/day. Polycystic ovary syndrome– 1200 mg/day. Lithium-induced psoriasis– 6 grams/day.
IV Infants RDS– 80 mg/kg/day.
Improvement in area of use.
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