Treatment of acute otitis externa (AOE) caused by susceptible strains of Pseudomonas aeruginosa or Staphylococcus aureus.
Inhibits bacterial DNA synthesis by inhibiting the DNA gyrase enzyme.
Death of susceptible bacteria with resolution of infection.
Absorption: Minimal systemic absorption follows otic use.
Metabolism and Excretion: Unknown.
TIME/ACTION PROFILE (cessation of ear pain)
Use Cautiously in:
Local: ear pruritus
Misc: allergic reactions
* CAPITALS indicate life-threatening.
Underline indicate most frequent.
Otic: (Adults and Children) ≥1 yr) 4 drops in infected ear(s) twice daily for seven days. Up to 8 drops may be given as an initial dose if used with an otowick.
Suspension for otic use: 0.3% suspension 5 mL in 8 mL bottle
Resolution of signs and symptoms of acute otitis externa (AOE).
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