vitamin B complex with vitamin C

General

vitamin B complex with vitamin C

Oral

Trade Name(s)

  • Albee-T
  • Albee with C
  • Arcobee with C
  • B-Complex/Vitamin C
  • Beminal
  • Econo B & C
  • Enviro-Stress
  • Farbee with Vitamin C
  • Gen-bee with C
  • High Potency N-Vites
  • Nion B Plus C
  • Probec-T
  • Sublingual B Total Liquid
  • Surbex T
  • Surbu-Gen-T
  • Surplex-T
  • Therapeutic B Complex with C
  • ThexForte
  • T-Vites
  • Vicon-C
  • Viogen-C
  • Vita-Bee with C

Parenteral

Trade Name(s)

  • Key Plex
  • Neurodep
  • Vicam

Ther. Class.
vitamins

Pharm. Class.
water soluble vitamins

Indications

Treatment and prevention of vitamin deficiencies.

Action

Contain most or all of the B-complex vitamins (B1 , B2 , B3 , B5 , B6 , B12 ) and vitamin C, a diverse group of compounds necessary for normal growth and development that act as coenzymes or catalysts in numerous metabolic processes.

Therapeutic Effect(s):

Replacement of vitamins in patients who are deficient or at risk for deficiency.

Pharmacokinetics

Absorption: Well absorbed after oral administration. Some absorptive processes require cofactors (B12 ).

Distribution: Widely distributed; cross the placenta and enter breast milk.

Metabolism and Excretion: Used in various biologic processes. Excess amounts are excreted unchanged by the kidneys.

Half-life: Unknown.

TIME/ACTION PROFILE

ROUTEONSETPEAKDURATION
POunknownunknownunknown

Contraindication/Precautions

Contraindicated in:

  • Hypersensitivity to ingredients in preparations (benzyl alcohol, parabens, bisulfites, tartrazine).

Use Cautiously in:

Undiagnosed anemias.

Adverse Reactions/Side Effects

In recommended doses, adverse reactions are extremely rare

GU: bright-yellow urine

Misc: ANAPHYLAXIS (VITAMIN B1 -THIAMINE), allergic reactions to preservatives

* CAPITALS indicate life-threatening.
Underline indicate most frequent.

Interactions

Drug-Drug

Large amounts of vitamin B6  may interfere with the beneficial effect of  levodopa.

Route/Dosage

PO IV (Adults and Children): Amount sufficient to meet RDA for age group.

Availability

Tablets, capsules, sublingual liquidcontain vitamins B1  (6–50 mg); B2  (5–50 mg); B3  (20–150 mg); B5  (10–50 mg); B6  (4–50 mg); vitamin B12  (0–1000 mcg); and vitamin C (50–600 mg) per tablet, capsule, or mLOTC

In Combination with: folic acid, biotin, chromium, soy protein, brewers yeast, potassium, manganese, and zinc in multivitamin/mineral productsRx, OTC .

Injectioncontains vitamin B1  (50 mg), B2  (5 mg), B3  (125 mg), B5  (6 mg), B12  (1000 mcg), and vitamin C (50 mg/mL)

Assessment

  • Assess patient for signs of vitamin deficiency before and periodically during therapy. Assess nutritional status through 24-hr diet recall. Determine frequency of consumption of vitamin-rich foods. Therapy is limited to periods of high physiologic stress when patient is not able to ingest adequate vitamins orally.
  • Monitor patient for anaphylaxis (wheezing, urticaria, edema); contains thiamine.

Potential Diagnoses

Implementation

IV Administration

  • Continuous Infusion:  Usually administered as part of a large-volume parenteral admixture.
  • Y-Site Compatibility:
    • aminophylline
    • ampicillin
    • atropine
    • MORE...
      • betamethasone
      • calcium gluconate
      • cefazolin
      • chlorpromazine
      • clindamycin
      • cyanocobalamin
      • dexamethasone
      • digoxin
      • diphenhydramine
      • dopamine
      • droperidol
      • epinephrine
      • erythromycin
      • fentanyl
      • fluorouracil
      • furosemide
      • gentamicin
      • hydralazine
      • insulin
      • isoproterenol
      • lidocaine
      • magnesium sulfate
      • methoxamine
      • minocycline
      • morphine
      • norepinephrine
      • oxacillin
      • oxytocin
      • penicillin G
      • phytonadione
      • procainamide
      • prochlorperazine
      • propranolol
      • pyridostigmine
      • scopolamine
      • sodium bicarbonate
      • succinylcholine
      • trimetaphan
  • Y-Site Incompatibility:
    • diazepam
    • phenytoin

Patient/Family Teaching

Encourage patient to comply with diet recommendations of health care professional. Explain that the best source of vitamins is a well-balanced diet with foods from the four basic food groups.

Evaluation/Desired Outcomes

Prevention of or decrease in the symptoms of vitamin deficiencies.

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